MLL1/WDR5/Ash2L/RbBP5/DPY30 (MLL1/WARD Complex), FLAG, His-Tag Recombinant 51021 from BPS Bioscience, Inc.

Description

MLL1/WARD complex of human MLL1 (GenBank Accession No. NM_005933,) a.a. 3745-end with N-terminal His-tag and MW= 27 kDa, human WDR5 (GenBank Accession No. NM_017588), a.a. 22-end with N-terminal FLAG-tag and MW= 35 kDa, human Ash2L (GenBank Accession No. NM_001105214), a.a. 2-end with N-terminal His-tag and MW= 61 kDa, human RbBP5 (GenBank Accession No. NM_005057), a.a. 2-end with N-terminal His-tag and MW= 60 kDa, and human DPY30 (GenBank Accession No. NM_032574) a.a. 2-end with N-terminal His-tag and MW=12 kDa individually expressed in an E. coli expression system

Product Specs
ItemMLL1/WDR5/Ash2L/RbBP5/DPY30 (MLL1/WARD Complex), FLAG, His-Tag Recombinant
CompanyBPS Bioscience, Inc.
Price Pricing Info Supplier Page View Company Product Page
Catalog Number51021
Quantity50 µg
Conjugate/TagN-terminal FLAG-tag (WDR5), N-terminal His-tag (others)
Format45 mM Tris-HCl, pH 8.0, 124 mM NaCl, 2.4 mM KCl, 225 mM imidazole, 1 mM TCEP, 1 µM ZnCl₂, and 10% glycerol
Molecular Weight195 kDa (complex)
SpeciesHuman
Domain/Region/TerminusMLL 3745-end, WDR5 3745-end, other components 2-end
NCBI Full Gene NameWD repeat domain 5, RB binding protein 5, histone lysine methyltransferase complex subunit, ASH2 like, histone lysine methyltransferase complex subunit, lysine methyltransferase 2A, dpy-30 histone methyltransferase complex regulatory subunit
NCBI Gene AliasesMLL1A, Saf19, BIG-3, RBQ3, MLL1, HTRX1, Bre2, Cps25, SWD1, SWD3, ASH2L1, ASH2L2, CFAP89, ASH2, TRX1, HRX, BIG3, MLL, ALL-1, CXXC7, HDPY-30, WDSTS
TypeRecombinant Protein Complex
Source/Expression SystemE. coli
ApplicationsUseful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling